Alexandria Wailes has worked onstage, in front of the camera, and behind the scenes on numerous Broadway, off-Broadway, and regional productions, television shows, and films. She has served as an advisor for ASL theater-interpreted teams with Hands On and TDF and as a teaching artist bringing theater into classrooms. She has worked with Deaf West Theatre, Mixed Blood Theatre, Playwrights Horizon, the Public, Pasadena Playhouse, City Center NY, Ars Nova, and more. She danced and performed with the Heidi Latsky Dance company and is a co-founder of BHo5.org as well as a member of the Forest of Arden company.

Wailes has spent many years advocating for Deaf and disability rights within the performing arts. She currently serves on the Dance/NYC disability task force as well as the creative advisory board of Perelman Performing Arts Center, and on the board of the National Theatre of the Deaf. She received a 2022 Chita Rivera for Outstanding Ensemble on Broadway for For Colored Girls, a 2020 Obie Citation for Sustained Excellence as an Artist and Advocate and a Lortel nomination for Outstanding Featured Actress in a Play for For Colored Girls.. at the Public. She appeared in Deaf West’s Spring Awakening and Big River (which was a Tony honoree for Ensemble), in Playwright Horizons' I Was Most Alive With You, and New York Live Arts' A Kind Of Alaska. She also appeared in the film The Hyperglot and on TV in “Law & Order: Criminal Intent,” “High Maintenance,” “Little America,” and “Nurse Jackie.” She is a proud member of AEA, SAG-AFTRA, and SDC.